Figure 7. TβRII siRNA inhibits the morphological fibroblast-like change of SRA01/04 cells. Inverted microscope images observing cell morphology of HLECs (A), cells treated for 48 h with scrambled siRNA (B), or cells treated for 48 h with 80 nM hT3 (C). Untreated control and scrambled RNA transfected cells were proliferated adhesively (A and B). By contrast, the proliferation of cells that transfected with 80 nM hT3 cells (C) was significantly suppressed. Transfected HLECs showed apoptotic changes such as condense of nucleus and lessened volume relative to untreated control and scrambled RNA transfected cells. The latter exhibited a fibroblast-like morphology obviously. The bar represents 25 μm.