Figure 2. Histology of corneas on days 1, 3, 7, 14, and 30 post–Candida albicans keratitis induction. Five corneas belonging to each Candida albicans keratitis (CaK) group were serially sectioned at each time point and adjacent sections were stained using the hematoxylin and eosin (H&E) and periodic acid–Schiff (PAS) methods. H&E staining was mainly used for examination of the cellular distribution and gross structure of the cornea, and PAS staining for revealing the distribution of fungi. One representative section from each group at each time point is shown. A: Structures of infected corneas changed significantly with time. B: Lasting infiltration in corneas of both sham and infected C57BL/6 mice, but only transient infiltration in Balb/c corneas as indicated for day 30.