Table 3 of Kandpal, Mol Vis 2012; 18:1123-1146.


Table 3. Alterations in the levels of crystallin transcripts in diabetic retinopathy and the reversal of their levels by RAGE inhibitor and p38 MAPK inhibitor.

    Fold change* Fold change* Fold change*
Gene symbol Gene name D vs N D + mRAGE-Fc vs N D + PHA666859 vs N
Crybb2 Crystallin, Beta B2 19.8 3.6 2.4
Cryba1 Crystallin, Beta A1 19.3 3.7 1.9
Cryba4 Crystallin, Beta A4 18.3 3.8 2.4
Crygs Crystallin, Gamma S 18.2 3.9 2.5
Cryaa Crystallin, Alpha A 17.9 3.5 2.4
Cryba2 Crystallin, Beta A2 16.4 3.4 2.1
Crybb1 Crystallin, Beta B1 15.1 3.9 2.8
Crybb3 Crystallin, Beta B3 9.2 3.2 2.5
Cryab Crystallin, Alpha B 6.6 3.6 1.9
Crygb Crystallin, Gamma B 4.5 3.2 2.2
Crygd Crystallin, Gamma D 3.9 2.6 2.3
Crygc Crystallin, Gamma C 2.4 1.7 1.6
Crygn Crystallin, Gamma N 1.6 1.5 1.2