Molecular Vision: Gibson, Mol Vis 2012; 18:1083-1092. Table 1

Table 1. Demographic information on patients and controls of POAG discovery and replication samples.

Descriptive	Discovery sample POAG cases	Replication sample POAG cases	p-value differences between discovery and replication samples	WTCCC2 controls	Southampton controls
No. of subjects	n=387	n=294		n=5380	n=50
Diagnosis
POAG	387	294		NA	0 (0%)
HTG	319(82%)	233(79%)		NA	0 (0%)
NTG	68(18%)	61(21%)	p=0.3†	NA	0 (0%)
Age in years
Mean	75.3	73.1		NA	79
Standard deviation	10.6	10.7	p=0.0077*	NA	4.9
Gender
Female	193	144		2647	27
Male	194	150	p=0.82†	2733	23

This table describes the diagnosis, age and gender of the discovery and replication POAG case and control samples. POAG=primary open-angle glaucoma; HTG=high tension glaucoma, NTG=normal tension glaucoma; p-value *significance of independent samples T- test, †significance of 2×2 χ² test; NA=not available. WTCCC2=Wellcome Trust Case Control Consortium 2 controls –including 1958 British birth cohort and national blood service cohort members. Southampton Controls –have no sign of Glaucoma or Age-related macular degeneration.