Table 8 of Khandelwal, Mol Vis 2012; 18:1055-1067.


Table 8. DHT impact on KEGG pathways in human meibomian gland epithelial cells.

KEGG Pathway DHT Genes ↑ Plac Genes ↑ DHT z-score Plac z-score
Lysosome 26 7 5.76 −1.06
Oxidative phosphorylation 21 8 4.3 −0.57
Peroxisome 16 3 4.24 −1.48
Aldosterone-regulated sodium reabsorption 9 2 3.41 −0.83
Insulin signaling pathway 21 9 3.35 −0.82
mTOR signaling pathway 10 3 3.18 −0.67
PPAR signaling pathway 12 3 3.01 −1.24
DNA replication 1 19 −1.05 9.94
Spliceosome 4 39 −1.93 9.2
Cell cycle 5 36 −1.53 8.41
Mismatch repair 1 11 −0.51 7.22
RNA transport 12 27 0.14 4.27
p53 signaling pathway 7 15 0.79 4.03
Small cell lung cancer 8 17 0.61 3.89