Table 8 of
Khandelwal, Mol Vis 2012; 18:1055-1067.
Table 8. DHT impact on KEGG pathways in human meibomian gland epithelial cells.
| KEGG Pathway | DHT Genes ↑ | Plac Genes ↑ | DHT z-score | Plac z-score |
|---|---|---|---|---|
| Lysosome | 26 | 7 | 5.76 | −1.06 |
| Oxidative phosphorylation | 21 | 8 | 4.3 | −0.57 |
| Peroxisome | 16 | 3 | 4.24 | −1.48 |
| Aldosterone-regulated sodium reabsorption | 9 | 2 | 3.41 | −0.83 |
| Insulin signaling pathway | 21 | 9 | 3.35 | −0.82 |
| mTOR signaling pathway | 10 | 3 | 3.18 | −0.67 |
| PPAR signaling pathway | 12 | 3 | 3.01 | −1.24 |
| DNA replication | 1 | 19 | −1.05 | 9.94 |
| Spliceosome | 4 | 39 | −1.93 | 9.2 |
| Cell cycle | 5 | 36 | −1.53 | 8.41 |
| Mismatch repair | 1 | 11 | −0.51 | 7.22 |
| RNA transport | 12 | 27 | 0.14 | 4.27 |
| p53 signaling pathway | 7 | 15 | 0.79 | 4.03 |
| Small cell lung cancer | 8 | 17 | 0.61 | 3.89 |