Table 3 of Khandelwal, Mol Vis 2012; 18:1055-1067.


Table 3. Influence of DHT on gene expression ratios in immortalized human conjunctival epithelial cells.

Accession # Gene Ratio p value Ontology
DHT>Placebo
NM_004994 Matrix metallopeptidase 9 10.9 0.00000 proteolysis
NM_001012964 Kallikrein-related peptidase 6 10.5 0.00001 proteolysis
NM_001323 Cystatin E/M 10.4 0.00002 epidermis development
NM_003856 Interleukin 1 receptor-like 1 9.0 0.00006 immune response
NM_018043 Anoctamin 1, calcium activated chloride channel 8.0 0.00001 ion transport
NM_002153 Hydroxysteroid (17β) dehydrogenase 2 7.8 0.00000 steroid biosynthetic process
NM_005416 Small proline-rich protein 3 7.4 0.00023 epidermis development
NM_144947 Kallikrein-related peptidase 11 7.2 0.00003 proteolysis
NM_001077491 Kallikrein-related peptidase 5 7.1 0.00018 proteolysis
NM_198129 Laminin, α3 5.6 0.00001 epidermis development
Placebo > DHT
NM_002993 Chemokine (C-X-C motif) ligand 6 12.4 0.00005 chemotaxis
NM_003186 Transgelin 10.8 0.00013 muscle organ development
NM_002974 Serpin peptidase inhibitor, clade B, member 4 10.1 0.00000 immune response
NM_001733 Complement component 1, r subcomponent 9.4 0.00012 proteolysis
NM_005602 Claudin 11 8.8 0.00005 cell adhesion
NM_006820 Interferon-induced protein 44-like 8.5 0.00001 immune response
NM_016352 Carboxypeptidase A4 8.4 0.00033 proteolysis
NM_003641 Interferon induced transmembrane protein 1 8.0 0.00001 cell surface receptor linked signaling pathway
NM_001710 Complement factor B 7.7 0.00000 proteolysis
NM_001044391 Mucin 1, cell surface associated 3.1 0.00127 protein binding