Figure 2. Blue light damage caused disorganization of photoreceptor outer segments. Confocal laser scanning microscope images of 5,5′,6,6’-tetrachloro-1,1’,3,3′-tetraethylbenzimidazol-carbocyanine iodide (JC-1) fluorescence in outer segments in a living murine retinal explant by 3-D reconstruction comprising serial confocal sections are presented of an undulating portion of the retina. Representative images of photoreceptor outer segments are provided for a three-hour untreated control (A) and a sample (B) that was irradiated for three hours with blue light with an output power of 1 mW/cm2. All units are 8.8 µm.