Figure 5. Dose-dependent protective effect of SP600125 against retina changes induced by intraocular pressure (IOP) elevation (45 mmHg) for 7 h. A: Representative images of hematoxylin and eosin-stained retinal cross-sections of eyes subjected to the different treatments. Thicknesses of the overall retina (B), inner retinal layer (C), ONL (D), OPL (E), INL (F), and cell density in the GCL (G) were quantified and are shown. Bars represent mean±SEM *: p<0.001 versus the “Control + Vehicle” group using a one-way ANOVA and a Dunnett’s test.