Figure 1. Pedigrees of families in which a
rhodopsin mutation was identified. The mutation p.Y178C (B) and
the mutation p.P347L (E) were segregated with disease phenotype.
The newly identified mutation p.A298D (D) was found in a
sporadic patient (II-3). Black and white symbols indicate affected and
unaffected individuals, respectively. The mutation is represented by
“m”; wild-type alleles are represented by “+”; arrows indicate probands.