Table 4 of Yip, Mol Vis 2011; 17:810-821.
Table 4. Pooled DNA analysis of tag SNPs in the COL11A1, COL18A1, FBN1, and PLOD1 genes.
Estimated freq of 1st allele in DNA pools | |||||||
---|---|---|---|---|---|---|---|
Candidate gene |
SNP* |
Alleles† (1st/2nd) |
k correction factor peak height ratio (1st/2nd) |
Case |
Control |
Diff Case - Control) |
Nested ANOVA p value |
COL11A1 | rs2061705 | C/T | 1.07 | 0.7361 | 0.7608 | −0.0247 | 0.3690 |
rs2615987 | C/A | 0.68 | 0.8228 | 0.8496 | −0.0268 | 0.1317 | |
rs17127311 ‡ | G/A | 0.77 | 0.1084 | 0.1409 | −0.0325 | 0.0981 | |
rs12143740 | C/T | 1.01 | 0.1041 | 0.0929 | 0.0112 | 0.6521 | |
rs4908273 | G/A | 0.91 | 0.7256 | 0.7165 | 0.0091 | 0.6941 | |
rs11164630 | G/A | 1.02 | 0.4140 | 0.3929 | 0.0211 | 0.3243 | |
rs9659030 | G/A | 1.05 | 0.2926 | 0.3079 | −0.0153 | 0.6075 | |
COL18A1 | rs11089001 | C/T | 1.07 | 0.5161 | 0.5292 | −0.0131 | 0.4837 |
rs2026885 | G/A | 1.09 | 0.6748 | 0.6798 | −0.0050 | 0.8748 | |
rs1004133 | G/A | 1.56 | 0.7386 | 0.7453 | −0.0067 | 0.8369 | |
rs2838907 | C/G | 1.14 | 0.6709 | 0.6721 | −0.0012 | 0.9681 | |
rs2838913 | G/A | 0.29 | 0.9246 | 0.9516 | −0.0270 | 0.1642 | |
rs2838916 | G/T | 0.97 | 0.5042 | 0.5038 | 0.0004 | 0.9864 | |
rs2838917 | G/A | 0.88 | 0.5840 | 0.5627 | 0.0213 | 0.4705 | |
rs2838920 | C/T | 1.21 | 0.6460 | 0.6468 | −0.0008 | 0.5991 | |
rs2838922 ‡ | C/T | 1.14 | 0.7680 | 0.7313 | 0.0367 | 0.0572 | |
rs2838923 | G/A | 0.83 | 0.4811 | 0.4706 | 0.0105 | 0.6356 | |
rs11911327 ‡ | C/T | 1.09 | 0.7656 | 0.7971 | −0.0315 | 0.0959 | |
rs8126757 | G/A | 0.92 | 0.5004 | 0.5158 | −0.0154 | 0.4029 | |
rs11702782 | G/A | 0.95 | 0.8379 | 0.8275 | 0.0104 | 0.5183 | |
rs2026887 | C/T | 0.94 | 0.5781 | 0.5890 | −0.0109 | 0.6956 | |
rs8129539 | C/G | 1.17 | 0.7152 | 0.6878 | 0.0274 | 0.2946 | |
rs8133622 | G/A | 1.02 | 0.3570 | 0.3572 | −0.0002 | 0.9847 | |
rs7279077 | T/A | 1.02 | 0.2285 | 0.2334 | −0.0049 | 0.8037 | |
rs2236454 ‡ | C/T | 0.57 | 0.5775 | 0.6285 | −0.0510 | 0.0629 | |
rs2236457 ‡ | C/T | 1.12 | 0.7031 | 0.6776 | 0.0255 | 0.0779 | |
rs2230687 | C/G | 1.17 | 0.6553 | 0.6423 | 0.0130 | 0.4992 | |
rs2236475 ‡ | G/A | 1.14 | 0.2955 | 0.3322 | −0.0367 | 0.0852 | |
rs7279445 | C/T | 0.86 | 0.5650 | 0.5648 | 0.0002 | 0.9832 | |
rs3753019 | C/T | 1.09 | 0.6069 | 0.6164 | −0.0095 | 0.7198 | |
rs2838951 | G/C | 1.17 | 0.4213 | 0.4260 | −0.0047 | 0.7522 | |
rs7499 | G/A | 0.97 | 0.5045 | 0.4767 | 0.0278 | 0.4194 | |
rs1051296 | G/T | 1.14 | 0.5576 | 0.5573 | 0.0003 | 0.9858 | |
FBN1 | rs6493334 | T/A | 0.97 | 0.6390 | 0.6384 | 0.0006 | 0.9738 |
rs6493333 | G/A | 1.09 | 0.7846 | 0.8116 | −0.0270 | 0.1682 | |
rs6493331 | G/T | 0.97 | 0.7304 | 0.7260 | 0.0044 | 0.8532 | |
rs2247876 | G/A | 1.06 | 0.1589 | 0.1830 | −0.0241 | 0.2860 | |
rs16961274 | C/G | 1.09 | 0.7850 | 0.7630 | 0.0220 | 0.4914 | |
rs12438332 | C/G | 1.14 | 0.8878 | 0.9112 | −0.0234 | 0.2146 | |
rs1807301 | C/T | 1.11 | 0.3600 | 0.3805 | −0.0205 | 0.2644 | |
rs16961207 | G/T | 1.15 | 0.7887 | 0.7972 | −0.0085 | 0.6213 | |
rs12915677 | G/A | 1.11 | 0.6875 | 0.6756 | 0.0119 | 0.6227 | |
rs683282 | G/A | 1.06 | 0.6829 | 0.6902 | −0.0073 | 0.7380 | |
rs16961118 | G/A | 0.89 | 0.8019 | 0.7978 | 0.0041 | 0.8580 | |
rs6493328 | C/T | 1.07 | 0.5318 | 0.5100 | 0.0218 | 0.3937 | |
rs17361868 | G/A | 0.99 | 0.7825 | 0.8030 | −0.0205 | 0.1928 | |
rs11635140 | G/A | 1.13 | 0.7071 | 0.7037 | 0.0034 | 0.8172 | |
rs11070643 | G/A | 1.00 | 0.7054 | 0.6942 | 0.0112 | 0.3992 | |
rs3825963 | C/T | 1.10 | 0.7603 | 0.7988 | −0.0385 | 0.1403 | |
rs10519174 | C/T | 0.94 | 0.6281 | 0.6329 | −0.0048 | 0.8305 | |
rs1467953 | C/A | 1.33 | 0.6339 | 0.6361 | −0.0022 | 0.7903 | |
PLOD1 | rs1208984 | G/A | 0.97 | 0.2559 | 0.2616 | −0.0057 | 0.8053 |
rs7529452 | C/T | 1.03 | 0.6258 | 0.5912 | 0.0346 | 0.4005 | |
rs7551175 | G/A | 1.14 | 0.7086 | 0.6950 | 0.0136 | 0.6240 | |
rs11585018 | G/A | 0.92 | 0.8047 | 0.7888 | 0.0159 | 0.5827 | |
rs2273286 | G/A | 0.99 | 0.1953 | 0.1947 | 0.0006 | 0.9778 | |
rs1130529 | C/T | 0.93 | 0.5770 | 0.5978 | −0.0208 | 0.6025 | |
rs2273291 | C/T | 1.05 | 0.6965 | 0.7189 | −0.0224 | 0.3443 | |
rs3818157 | G/A | 1.19 | 0.3911 | 0.3726 | 0.0185 | 0.4668 | |
rs3753579 | G/A | 1.06 | 0.4766 | 0.4494 | 0.0272 | 0.3591 |