Figure 1. Single nucleotide polymorphisms (SNPs) and their linkage disequilibrium (LD) for the COL18A1 gene. The SNPs are indicated from the 5′ end (left) to the 3′ end (right) of the gene. The LD measures are expressed as D’ and r² for all subjects under study (cases and controls combined), and are calculated by Haploview. The shades of red (for D’) and gray (for r²) represent the magnitude of the measures with deep red equal to 100% (or 1.00), which is omitted in the diagram to avoid cluttering.