Figure 1. Corneal NV induced by alkali burn. A: slit-lamp photograph of corneal NV on the 10th and 14th days after chemical cauterization. The NV of the PBS-treated group was dense, fine, and almost reached to the central cornea. The NV of all KH906-treated groups and the Avastin-treated group was less dense and shorter than that of the PBS group. The inhibitive effect on NV in the dexamethasone-treated group was the best. B: The length of the longest vessel in all groups on the 10th and 14th days. The mean length of the longest new vessel in all medicine-treated groups was shorter than that of the PBS control group on both the 10th and 14th days after cauterization (p<0.05). The vessel length was shortest in both the dexamethasone-treated group and the KH906 (20 mg/ml)-treated group, and there was a statistically significant difference between the two groups and the other groups on the 10th day (p<0.05). Meanwhile, only the length of the longest vessel in the dexamethasone-treated group differed significantly from those of the other medicine-treated groups on the 14th day (p<0.05). C: Area of corneal NV in all groups on the 10th and 14th days. The change in the area of corneal NV showed the same trend as that of the length of the longest new vessel. PBS: PBS, DEX: dexamethasone, AV: Avastin, K-5:KH906 (5 mg/ml), K-10:KH906 (10 mg/ml), K-20:KH906 (20 mg/ml). *There is a statistically significant difference between groups with a *symbol and groups without a *symbol. #There is a statistically significant difference between groups with a #symbol and groups without a #symbol.