Figure 2. CRYGC DNA sequence in an affected and an unaffected individual. A: DNA sequence electropherogram of an unaffected individual showing wild type G at position 181. B: DNA sequence electropherogram showing the heterozygous 181G>A substitution that replaces Arginine by Histidine at codon 48 in the affected individual. The position of mutated (G>A) and wild type nucleotide G in an affected and an unaffected individual is indicated in box.