Figure 7. Light micrographs of plastic-embedded mouse posterior sclera. Photomicrograph of posterior scleral thickness of spectacle lens treated (A) and control sclera (B). Normal saline treated myopic (C) and contra-lateral control eyes (D, n=6 eyes, 6 sections from each eye), 40× original magnification. There was no effect of normal saline on the posterior scleral thickness of myopic sclera. Lens treatment with and without normal saline reduced the sclera thickness which shows that scleral thinning occurred during myopia development and there was no effect of normal saline treatment in the myopia progression. Atropine treated myopic (E) and atropine treated contra-lateral control eyes (F, n=6 eyes, 6 sections from each eye), 40× original magnification. Atropine sulfate was increased the posterior scleral thickness which shows that 1% atropine was effective in the myopia progression in mouse. Arrow indicates the sclera and box indicates the thickness. Scale bar=50 μm. Black arrows indicate the sclera and white circles show the scleral fibroblasts.