Figure 2. Atropine sulfate (pan muscarinic antagonist) and normal saline treated BJ mice ocular biometry measurements were plotted against induction period (weeks). One group was treated with sub-conjunctival injection of 1% atropine sulfate (pan muscarinic antagonist) and another group was treated with 0.9% normal saline for four weeks. The drug treatment was started after 2 weeks of minus lens wearing. Four weeks after drug treatment, refractive error and ocular biometry determined as before. The corneal thickness (A) and anterior chamber depth (B) was not significantly different with or without drug treatment. The lens thickness (C), vitreous chamber depth (D) and axial length (E) were significantly reduced after receiving atropine and there was no effect with saline treatment. The myopic eye received atropine sulfate was shifted from myopic to hyperopic when compared to saline treated myopic eye was till at myopic shift (F). There was no significant difference seen in the control eyes. Spectacle lens-induced myopic eye received 1% atropine reduced the myopia progression and not with saline treatment. This result confirms that 1% atropine reduces myopia progression in mice. Data was represented as mean±S.D, * represents significance level p<0.05 and ** represents significance level p<0.01.