Figure 1. This graph represents the ocular biometry of Balb/CJ (BJ) and C57BL/6 (B6) mice with −10 D spectacle lens induced myopia.
The lens was applied at post-natal day 10 (before eye opening). The ocular biometry measurements were measured using OLCI-AcMaster
(in vivo: accuracy ±10 microns) and refraction (diopters) was measured by automated infrared photorefractor at 2 weeks, 4
weeks, and 6 weeks after induction of myopia. The BJ and B6 mice ocular biometry measurements (mm) were plotted against lens
weraing period (weeks). The corneal thickness (A) and anterior chamber depth (B) was not significantly different when comparing the lens treated eyes against contra-lateral control eyes in both strains.
The lens thickness (C), vitreous chamber depth (D), axial length (E), and refraction (F) were significant after 4 weeks and 6 weeks of induction in both strains. However when comparing the both strains, Balb/CJ
mice eyes were more significant (n=50, p<0.01) at 6 weeks of minus lens wearing. Spectacle lens-induced myopia caused elongation
of the globe and reduced hyperopia. Data was represented as mean±S.D, * represents significance level p<0.05 and ** represents
significance level p<0.01.