Figure 3. Effect of myopia induction on the expressions of BMPs in guinea pigs sclera. A: Significant decreases in mRNA expression were found in BMP-2 and BMP-5 compared with the internal control eyes. C: contralateral control, F: form-deprivation myopia. B: western blotting also showed a significant decrease for BMP-2 and BMP-5 but not for BMP-4. Bar graph shows changes in mRNA and protein expressions of BMP subtypes in the posterior sclera during form-deprived myopia in guinea pigs. Values (mean±standard error of the mean) were expressed as relative expression levels. The asterisk denotes a p<0.05.