Figure 2. Cross species conservation analysis. The black bars highlight the interesting positions of the proteins. A: Multiple alignment indicates that valine at position 139 in gap junction protein α3 (GJA3) is medium conserved. B: Valine at codon 275 in gap junction protein α8 (GJA8) is highly conserved. C: At lens intrinsic membrane protein 2 (LIM2) position 23, methionine was not a conserved amino acid residue compared to threonine.