Table 2 of Mossböck, Mol Vis 2011; 17:616-620.


Table 2. Genotype distribution and allele frequency of the CYP46A1 IVS2 –150 C>T polymorphism (rs754203) in patients with primary open angle glaucoma (POAG) with early (mean defect [MD] above −6 dB), moderate (MD between −6 and −12 dB) and severe (MD below −12dB) defect.



Genotype
Patients with
early defect
(n=59)
Patients with
moderate defect
(n=87)
Patients with
severe defect
(n=127)
Control
subjects
(n=251)

Significance
p-value
rs754203
 TT 26 (44.1) 34 (39.1) 52 (40.9) 120 (47.8) 0.60; 0.16; 0.21*
TC 26 (44.1) 43 (49.4) 63 (49.6) 112 (44.6)  
CC 7 (11.8) 10 (11.5) 12 (9.4) 19 (7.6)  
rs754203
 C-allele frequency 0.339 0.362 0.343 0.299 0.39; 0.12; 0.22