Table 1. Genotype distribution and allele frequency of the CYP46A1
IVS2 –150 C>T polymorphism (rs754203) in
patients with primary open angle glaucoma (POAG).
Genotype |
Patients with
POAG
(n=330) |
Control
subjects
(n=251) |
Significance
p-value |
rs754203
TT |
136 (41.2) |
120 (47.8) |
0.20 |
TC |
161 (48.8) |
112 (44.6) |
|
CC |
33 (10.0) |
19 (7.6) |
|
rs754203
C-allele frequency |
0.344 |
0.299 |
0.10 |