Figure 3. Comparison of expressional characteristics between primary melanomas and their corresponding cell lines. Normalized expressional values from Affymetrix GeneChip HG U133 plus 2.0 arrays for 25 genes significantly upregulated in monosomy 3 tumors and 20 genes significantly down-regulated or silenced in monosomy 3 melanomas compared to melanomas with 6p gain in the absence of chromosome 3 loss were selected to compare expressional variation between primary tumor biopsies and the corresponding cell lines. A: MEL20–06–039; B: MEL20–07–070; C: MEL20–06–045 cell line is shown in combination with MEL20–06–039 and MEL20–07–070 to provide a comparison of this cell line’s expressional profile with those for which primary tumor expressional characteristics are known. Probeset identifiers and genomic locations of the listed genes are detailed in Table 2.