Figure 2. Comparison of Mapping Array results for chromosomal copy number for primary tumor biopsies and their cell lines, where available. Copy number variation analysis, as determined by Affymetrix Genotyping Console, showed identical patterns of aberration between primary tumor biopsies and corresponding cell lines. Gains (green boxes) and losses (red boxes) were largely whole arm in extent. 2± designations signify a total of 4 or more copies of chromosome 8q were detected. All samples had monosomy 3, 6q loss, 8p loss, multiple gains in 8q, and 16q loss. MEL20–06–045 and MEL20–07–070 also had 6p gain.