Figure 1. Morphological changes of the equatorial capsule (containing adherent epithelial cells) of the cultured rat lens. A: Control group; B: Dex group; C: RU486+Dex group. HE, original magnification 200×. A disordered arrangement of fiber cells was induced by treatment with dexamethasone (Dex) compared to the control. In the group treated with RU486 and Dex (RU486+Dex), no disruption was observed, which suggested that the morphological changes induced by Dex were blocked by RU486.