Figure 3. Mutation analysis from sporadic case (S1). A: Partial nucleotide sequences of FOXL2 from patient. The sequence showed an indel mutation, c.50delCinsTA (indicated by the arrow). This de novo mutation resulted in a frameshift mutation expected to cause miscoding of 78 amino acids from codon 17 and eventually a premature stop codon at 95. B: The parents and the control subjects lacked this change.