Figure 1. Cell proliferation analysis of bovine retinal capillary endothelial cells. Cell proliferation was significantly inhibited by asymmetric dimethylarginine (ADMA) for 24–72 h. In group A, bovine retinal capillary endothelial cells (BRCECs) were cultured in endothelial cell medium (ECM) with 0.4% fetal bovine serum (FBS). In groups B throught E, BRCECs were cultured in ECM with 0.4% FBS plus 10 μM, 50 μM, 100 μM, or 200 μM ADMA. Results are expressed as absorbance at 490 nm and represent means±SEM, n=8: *p<0.05 versus group A, **p<0.01 versus group A, #p<0.05 versus group B, ##p<0.01 versus group B, +p<0.05 versus group C, ++p<0.01 versus group C, &p<0.05 versus group D, &&p<0.01 versus group D.