Table 2 of Yanagisawa, Mol Vis 2011; 17:3574-3582.

Table 2. Allele and Genotype Distributions of the ARMS2 A69S Variant of Case-Control Studies Contributing to the Meta-Analysis

      Genotype (GG/GT/TT) Risk allele frequency  
Study Year Ethnicity Neovascular AMD PCV Control Neovascular AMD PCV Control PHWE*
[51] 2008 Japanese NA 15/49/45 39/32/14 NA 0.64 0.35 0.10
[52] 2008 Chinese NA 17/30/25 33/48/12 NA 0.56 0.39 0.51
[29] 2009 Japanese 18/30/52 18/50/32 85/84/20 0.67 0.57 0.33 1.0
[30] 2010 Japanese 67/155/183 122/216/171 502/638/196 0.64 0.55 0.39 0.82
[31] 2011 Japanese 6/20/24 22/20/18 64/58/16 0.68 0.47 0.33 0.70
This study 2011 Japanese 26/81/74 42/77/79 79/94/30 0.63 0.59 0.38 0.88

Abbreviations: ARMS2, age-related maculopathy susceptibility 2; AMD, age-related macular degeneration; PCV, polypoidal choroidal vasculopathy; HWE, Hardy–Weinberg equilibrium; NA, not available. *p values generated by the exact test for Hardy–Weinberg equilibrium.

Yanagisawa, Mol Vis 2011; 17:3574-3582. http://www.molvis.org/molvis/v17/a384

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