Figure 1. Pedigrees and genotypes of Israeli Arab families with USH1. Shown are four Israeli Arab families segregating USH1. Double lines indicate consanguineous unions. Filled symbols represent affected individuals, whereas clear symbols represent unaffected individuals. Mutation-bearing haplotypes are marked with black bars. A: Family TB86. Genetic analysis demonstrates co-segregation of an USH1C-linked haplotype and mutation (c.497–2delA) with USH1. B: Family TB114. Genetic analysis demonstrates co-segregation of a mutation of MYO7A (p.Q234X) with USH1. C: Family TB63. Genetic analysis demonstrates co-segregation of an USH1B-linked haplotype and a MYO7A mutation (c.1135–1147dup) with USH1. D: Family TB109. Genetic analysis demonstrates co-segregation of a mutation of USH1G (c.206–207insC) with USH1. m, mutant allele; +, wt allele.