Figure 1. Pedigree and homozygosity
mapping of KKESH205. A: Pedigree of the KKESH205 family
with LCA is shown. Affected, solid symbols; unaffected, open
symbols; squares, male; circles, female. B: Homozygosity
mapping of KKESH205 using high-density SNP arrays. The 11.2 Mb
region, which is located on chromosome 15 (red box), is the only
homozygous region shared by all three affected members in the
whole genome.