Figure 4. TL1A (TNFSF15) promoted secretion of IL-17 by CD4⁺ T cells. A: CD4⁺ T cells from the control, experimental autoimmune uveitis (EAU), and recovery phase mice were cultured in the presence of anti-CD3 (1 µg/ml) and anti-CD28 (1 µg/ml), with or without recombinant TL1A (100 ng/ml) for 72 h. IL-17 levels in the media were then determined with ELISA. B: The increased concentration of IL-17 secreted by CD4+ T cell in each group after TL1A stimulation for 72 h. Each value represents the mean±SD (n=6).