Figure 1 of Qin, Mol Vis 2011; 17:3486-3493.


Figure 1. Histopathologic features of the eyes enucleated from experimental autoimmune uveitis (EAU), recovery phase and control mice. A: Eye of CFA controls. Normal retinal structure in a B10.RIII mouse. Hematoxylin-eosin (H and E) staining (magnification, 200×). B: Eye of EAU mice. An image from mice day 14 after IRBP immunization (at the peak of inflammation) shows inflammatory T lymphocytes (horizontal arrows) and macrophages (vertical thin arrow) infiltrating the vitreous and the retina, vasculitis (vertical bold arrow), damage to the retinal photoreceptor cell layer (pounds) and granuloma (asterisk). H and E staining (magnification, 200×). C: Eye of recovery phase mice. An image from mice week 4–5 or more after IRBP immunization shows no obvious inflammation in the retina. H and E staining (magnification, 200×). D: Mean histopathologic score during the development of EAU. * indicates p<0.001 when compared EAU with control mice. Each value represents the mean±SD (n=6).