Figure 2. Protein sequence alignment. A: CRB1 L1047 amino acid(red) in ten species ranging from humans to zebrafish. L1047 is conserved in all species from Homo sapiens to Danio rerio as ascertained by a bioinformatic search of NCBI-Blast by means of human CRB1 DNA and protein and MegAlign (DNASTAR Lasergene,
Madison, WI). And this may indicate functional or structural significance in L1047. B: SPATA7 A313 amino acid(red) in ten species ranging from humans to mice. A313 is relatively conserved among mammal.