Figure 5 of Tan, Mol Vis 2011; 17:3300-3308.


Figure 5. The effect of amiloride or psalmotoxin 1 on retinal ganglion cell death induced by experimental hypoxia in vitro. Hypoxia significantly reduced the survival of cultured retinal ganglion cells (RGCs) to 18.5±8.7% (n=3), whereas amiloride treatment increased RGC survival to 72.3±12.6% (n=3). Although psalmotoxin 1 (PcTX1) did not affect the current amplitude induced by acid under normal conditions, PcTX1 treatment increased RGC survival to 36.9±13.7% (n=3) after 2 h of hypoxia (*p<0.05).