Figure 3. A: Representative images showing enhancement of the acid-induced [Ca²⁺]i elevation in cultured retinal ganglion cells (RGCs). B: Summary of results on the ASIC-mediated [Ca²⁺]i elevation. Dashed line indicates the basal level of fluorescence ratio (340/380). Inset, representative ratiometric measurements of [Ca²⁺]i elevation induced by a solution of pH 6.0. Data are mean±SEM (n=12 for each group). Asterisk indicates p<0.05, compared with the ratio induced by pH 7.4.