Table 3 of Wang, Mol Vis 2011; 17:3290-3299.

Table 3. Allele frequency and genotypes of the three SNPs in myopia cases and healthy controls. Myopia was classified as early onset high myopia and complex myopia.

SNPs Allele (A/B) Classification of subjects Number of subjects MAF Genotype p value* OR 95%CI
            A/A A/B B/B Allele Genotype    
rs2839471 C/T myopia complex (−10.00D≤S≤-4.00D) 1255 0.489 293 641 321 0.393 0.266 1.052 0.937–1.181
      early onset (S≤-6.00D) 563 0.472 116 300 147 0.838 0.131 0.985 0.852–1.139
      complex+early onset 1818 0.484 409 941 468 0.582 0.151 1.031 0.926–1.148
    healthy control −0.50D≤SE≤+2.00D 1052 0.476 248 506 298        
rs577948 A/G myopia complex (−10.00D≤S≤-4.00D) 1255 0.494 302 665 288 0.307 0.269 1.062 0.946–1.193
      early onset (S≤-6.00D) 563 0.491 123 307 133 0.973 0.282 1.003 0.867–1.159
      complex+early onset 1818 0.499 425 972 421 0.439 0.207 1.043 0.937–1.162
    healthy control −0.50D≤SE≤+2.00D 1052 0.49 251 530 271        
rs11218544 G/T myopia complex (−10.00D≤S≤-4.00D) 1255 0.401 200 607 448 0.032 0.098 1.14 1.012–1.284
      early onset (S≤-6.00D) 563 0.382 83 264 216 0.515 0.771 1.051 0.905–1.220
      complex+early onset 1818 0.395 283 871 664 0.061 0.17 1.112 0.995–1.242
    healthy control −0.50D≤SE≤+2.00D 1052 0.37 142 495 415        

Note: MAF=minor allele frequency; S=spherical refraction; SE=spherical equivalent. *P value was calculated by chi-square test between myopia and normal control.

Wang, Mol Vis 2011; 17:3290-3299. http://www.molvis.org/molvis/v17/a354

©2011 Molecular Vision http://www.molvis.org/molvis/

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