Molecular Vision: Rose, Mol Vis 2011; 17:3243-3253. Table 3

Table 3. Clinical details of South Indian POAG patients with MYOC mutations.

Patient	Mutation	Age (at diagnosis)	GON- C/D ratio		BCVA		GVFD		IOP (mm Hg) at diagnosis		Medication/ Surgery	Family history
			RE	LE	RE	LE	RE	LE	RE	LE
Eg-17	Gln48His	63	0.7	0.8	6/6	LPP	+	+	22	26	Medication	No
Eg-10	Gln48His	43	0.9	0.4	6/9	6/6	+	EBS	24.4	14.6	Medication	No
BSR-16*	Thr353Ile	14	0.9	1	6/9	NLP	+	Blind	21**	-	Surgery	Yes
BSR-16*	Asn480Lys	14	0.9	1	6/9	NLP	+	Blind	21**	-	Surgery	Yes
Ngl-12#	Ser331Thr	68	0.9	1	6/6	LPP	+	+	20.6	20.6	Medication	No
R-6#	ProLeu370	16	-	-	NLP	NLP	Blind	Blind	-	-	-	Yes

* - Undergone surgery when blood samples were collected at the age of 34. ** - IOP at sample collection (IOP data at diagnosis, not available). ^# - Published data [46]. Abbreviations: GVFD- Glaucomatous visual field defect; GON- Glaucomatous optic neuropathy; BCVA- Best corrected visual acuity, using Snellen chart, at time of sample collection; LPP- Light perception with projection; NLP- No light perception (blind); EBS- Enlarged blind spot.