Figure 2 of Roy, Mol Vis 2011; 17:3166-3174.


Figure 2. Dose response study showing fibronectin (FN)–siRNA efficacy. Different doses of FN-siRNA were tested at a 1-week time point to identify an optimal dosage for effective downregulation of FN expression. The graph shows reduced FN levels in rat retinas after intravitreal injection with increasing concentrations (0.5–6.0 μM) of FN–SiRNA. A 3 μM dose was most effective at downregulating retinal FN protein expression. *=p<0.05 versus “0 μM” group mean; n=4/group.