Table 3 of
Osborne, Mol Vis 2011; 17:3097-3106.
Table 3. Parental age at the birth of the anophthalmia subjects compared with parental age in the general population of births for England and Wales.
Parental age comparisons |
Number of anophthalmia subjects |
Parents of anophthalmia subjects |
Parental age at birth for the general population3 |
Difference in age (years) |
p value4 |
---|---|---|---|---|---|
Deletions | |||||
Median (range) paternal age in years | 8 | 30.0 (24.0–34.0) | 32.1 (30.0–32.2) | −2.11 | 0.19 |
Median (range) maternal age in years | 8 | 24.5 (21.0–30.0) | 27.5 (26.5–31.0) | −3.01 | 0.17 |
Mutations | |||||
Median (range) paternal age in years | 13 | 35.0 (18.0–44.0) | 31.7 (29.7–32.4) | +3.31 | 0.66 |
Median (range) maternal age in years | 15 | 31.0 (18.0–41.0) | 27.2 (25.1–32.4) | +3.81 | 0.05 |
Paternal age | |||||
Median (range) paternal age in years of subjects with deletions | 8 | 30.0 (24.0–34.0) | - | +5.02 | 0.22 |
Median (range) paternal age in years of subjects with mutation | 13 | 35.0 (18.0–44.0) | - | ||
Maternal age | |||||
Median (range) maternal age in years of subjects with deletions | 8 | 24.5 (21.0–30.0) | - | +6.52 | 0.05 |
Median (range) maternal age in years of subjects with mutation | 15 | 31.0 (18.0–41.0) | - |