Table 4 of Yang, Mol Vis 2011; 17:3088-3096.

Table 4. Haplotype association analysis between vascular endothelial growth factor (VEGF) polymorphisms and risk of diabetic retinopathy in patients with type 2 diabetes mellitus.

Haplotype blocks DR group (%) DWR group (%) OR (95%CI) χ2 p value
Block 1
CTG 69.3 77.4 0.66 (0.45, 0.97) 4.42 0.036
ACA 30.31 22.6 1.52 (1.03, 2.24) 4.42 0.036
Block 2
CGC 42.9 44.9 0.95 (0.67, 1.34) 0.1 0.76
GAC 24.2 32.1 0.69 (0.47, 1.01) 3.73 0.054
GAA 29.3 20.8 1.62 (1.08, 2.41) 5.59 0.018

Data were given as frequency of each haplotype within diabetic retinopathy (DR) group or diabetic without retinopathy (DWR) group. Block 1 included promoter SNPs rs699947, rs833061, and rs13207351, whereas block 2 included SNPs rs2010963 at 5′ UTR, rs833069 at intron 2, and rs2146323 at intron 2. Only haplotypes with frequency over 3% were included in this table. OR indicates odds ratio and CI refers to confidence interval.

Yang, Mol Vis 2011; 17:3088-3096. http://www.molvis.org/molvis/v17/a332

©2011 Molecular Vision http://www.molvis.org/molvis/

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