Figure 1. Linkage disequilibrium plot generated by Haploview 4.2 software. Two haplotype blocks (bold) were identified for single nucleotide polymorphisms (SNPs) in the vascular endothelial growth factor (VEGF) gene. Linkage disequilibrium (LD) is displayed as pairwise D’ values multiplied by 100 and given for each SNP combination [40]. Shading represents the magnitude and significance of pairwise LD, with a red-to-white gradient reflecting higher-to-lower LD values. Red diamond without a number corresponds to D’ values of 1.0.