Figure 5. The lop11 lens phenotype after P10. Between P10-P12 lop11 lenses develop vacuolated cataracts that result in the rupture of the lens capsule (B) and release of the lentricular material in the vitreal cavity (asterisk). The boxed areas are depicted at the higher magnification in C and D. The vacuoles develop between cortical and nuclear fiber cells as shown in D. The lop11 vacuolated cataracts are clinically visible following the eyelid opening between P12–14 (F) after which the cataract phenotype does not progress. In A and B, scale bars represent 200 µm; in C and D scale bars represent 20 µm.