Table 8 of
Brooks, Mol Vis 2011; 17:3034-3054. Table 8 of
Brooks, Mol Vis 2011; 17:3034-3054.
Table 8. Top 25 transcripts down-regulated in Nrl−/− retina compared to WT.
| Transcript | Gene ID | Gene name | WT FPKM | Nrl−/− FPKM | FC |
|---|---|---|---|---|---|
| NM_145383 | Rho | Rhodopsin | 8135.4 | 1.7 | −4803.93 |
| NM_008140 | Gnat1 | Guanine nucleotide binding protein γ transducing activity polypeptide 1 | 4011.7 | 2 | −2033.85 |
| NM_001136074 | Nrl | Neural retina leucine zipper | 545 | 1.9 | −284.05 |
| NM_007723 | Cnga1 | Intracellular cGMP activated cation channel | 232.3 | 1 | −229.13 |
| NM_013708 | Nr2e3 | Nuclear receptor subfamily 2 group E member 3 | 237.2 | 1 | −227.54 |
| NM_144813 | Slc24a1 | Solute carrier family 24 member 1 (sodium-potassium-calcium exchanger 1) | 263.2 | 3.2 | −81.57 |
| NM_145963 | Kcnj14 | Potassium inwardly-rectifying channel subfamily J member 14 | 63.6 | 1.4 | −44.02 |
| NM_139292 | Reep6 | Receptor accessory protein 6 | 317.4 | 8.6 | −36.76 |
| NM_025491 | Susd3 | Sushi domain containing 3 | 58.1 | 1.7 | −34.06 |
| NM_011934 | Esrrb (isoform 1) | Estrogen-related receptor β | 67.2 | 2.6 | −26.17 |
| NM_001007576 | Gucy2f | Guanylate cyclase 2f | 36.5 | 1.6 | −22.78 |
| NM_008806 | Pde6b | Phosphodiesterase 6B cGMP-specific rod β | 364.6 | 16.2 | −22.32 |
| NM_001195413 | Cngb1 | Cyclic nucleotide gated channel β 1 | 52.3 | 2.5 | −21.11 |
| NM_001160017 | Gnb1 (isoform 3) | Guanine nucleotide binding protein β polypeptide 1 | 487.8 | 24.4 | −19.97 |
| NM_008736 | Nrl | Neural retina leucine zipper | 20 | 1 | −19.97 |
| NM_008142 | Gnb1 (isoform 1) | Guanine nucleotide binding protein β polypeptide 1 | 349.7 | 17.9 | −19.7 |
| NM_007472 | Aqp1 | Aquaporin 1 | 42.5 | 2.2 | −19.56 |
| NM_001160016 | Gnb1 (isoform 2) | Guanine nucleotide binding protein β polypeptide 1 | 352.1 | 18.1 | −19.29 |
| NM_153803 | Glb1l2 | Galactosidase, β 1-like 2 | 55.7 | 3.5 | −16.11 |
| NM_001159500 | Esrrb (isoform 2) | Estrogen-related receptor β | 22.5 | 1.5 | −15.03 |
| NM_172802 | Fscn2 | Fascin homolog 2, actin-bundling protein, retinal | 41.6 | 3 | −14.03 |
| NM_001033498 | Gramd2 | Member of the GRAM domain containing family | 20.3 | 1.4 | −14.03 |
| NM_027001 | 2610034M16Rik | Unknown | 69.6 | 5.1 | −13.64 |
| NM_018865 | Wisp1 | WNT1 inducible signaling pathway protein | 17.8 | 1.4 | −12.21 |
| NM_146086 | Pde6a | Rod photoreceptor cGMP phosphodiesterase α subunit | 433.5 | 35.8 | −12.13 |