Table 1 of Heynen, Mol Vis 2011; 17:2934-2946.

Table 1. Mouse models of inherited retinal degeneration used in this study


Animal
model

Gene
Mutation/
Transgene		 Time
course of
degeneration		 Model
for
disease

Origin

Reference
Rd1 Pde6b Nonsense PND8–21 arRP Harlan, Horst, The Netherlands [4]
Rd10 Pde6b Missense PND16–60 arRP Jackson Laboratory, Bar Harbor, ME [5]
VPP Rho Tg(V20G,P23H,P27L) PND20–250 adRP Dr. Muna Naash [6]

Abbreviations: Pde6β: Phosphodiesterase 6β; Rho: Rhodopsin; adRP: autosomal dominant retinitis pigmentosa, arRP: autosomal recessive retinitis pigmentosa, Rd: retinal degeneration, PND: postnatal day, Tg: transgene.

Heynen, Mol Vis 2011; 17:2934-2946. http://www.molvis.org/molvis/v17/a317

©2011 Molecular Vision http://www.molvis.org/molvis/

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