Table 2 of
Xia, Mol Vis 2011; 17:2920-2933. Table 2 of
Xia, Mol Vis 2011; 17:2920-2933.
Table 2. Canonical pathway–based analyses of gene expression data in retinas, KEGG was used to identify the genes significantly associated with canonical pathways in the KEGG pathways database.
| Name | p value | Genes involved (p<0.05. Fold change>2) |
|---|---|---|
| Allograft rejection | 0 | FAS, MAMU-A, MAMU-B18, MAMU-I |
| Antigen processing and presentation | 0 | B2M, MAMU-A, MAMU-B18, MAMU-I, LOC719379, LOC717726 |
| Complement and coagulation cascades | 0.0119 | C1S, SERPING1 |
| Graft-versus-host disease | 0 | FAS, MAMU-A, MAMU-B18, MAMU-I |
| P53 signaling pathway | 0.001 | DDB2, FAS, GADD45B, |
| Type I diabetes mellitus | 0 | FAS, MAMU-A, MAMU-B18, MAMU-I |
| Autoimmune thyroid disease | 0.0004 | FAS, MAMU-A, MAMU-I, MAMU-B18 |
| Viral myocarditis | 0.0028 | MAMU-A, MAMU-B18, MAMU-I |
| Endocytosis | 0.0021 | MAMU-A, MAMU-B18, MAMU-I, PSD2 |
| Cell adhesion molecules(CAMs) | 0.0069 | MAMU-A,MAMU-B18,MAMU-I, CLDN18 |
| Natural killer cell mediated cytotoxicity | 0.0007 | FAS,MAMU-A,MAMU-B18,MAMU-I |
| Cytokine-cytokine receptor interaction | 0.0004 | CCL8,CXCL10, FAS,IL7,OSMR,MCP-1,CLDN18 |
| Primary immunodeficiency | 0.0041 | BLNK, LOC717726 |
| RIG-I-like receptor signaling pathway | 0.0007 | CXCL10, IFIH1,ISG15 |
| NOD-like receptor signaling pathway | 0.0016 | CCL18, MCP-1 |
| Chemokine signaling pathway | 0.0128 | CCL8, CXCL10, MCP-1 |
| Peroxisome | 0.0165 | GNPAT, LOC574097 |
| MAPK signaling pathway | 0.0269 | BDNF, FAS, GADD45B |
| Primary bile acid biosynthesis | 0.0385 | CH25H |