Table 3 of Leema, Mol Vis 2011; 17:2889-2897.

Table 3. Correlation between aflatoxin production and relative expression of the regulatory (aflR and aflJ) and structural (nor-1 and pksA) aflatoxin biosynthetic pathway genes.



Fungal strains of A. flavus

Gene		 Relative gene
expression
levels*		 Quantum of
aflatoxin
production**		 Pearsons
correlation
coefficient

p value

significance
Corneal aflatoxigenic aflR 1.0384±0.0844 305.63±96.6 0.856 0.030 Significant
  aflJ 1.1295±0.0955   0.679 0.138 Not significant
  nor-1 0.9181±0.0398   0.644 0.167 Not significant
  pksA 0.8805±0.0325   0.576 0.232 Not significant
Environmental aflatoxigenic aflR 0.9508±0.0609 210.16±11.34 0.844 0.035 Significant
  aflJ 1.0526±0.0854   0.946 0.004 Significant
  nor-1 0.8552±0.0332   0.958 0.003 Significant
  pksA 0.8716±0.03343   0.964 0.002 Significant
All aflatoxigenic strains aflR 0.9946±0.0838 257.898±82.38 0.829 0.001 Significant
  aflJ 1.0911±0.0952   0.671 0.017 Significant
  nor-1 0.8679±0.0340   0.622 0.031 Significant
  pksA 0.8948±0.0426   0.678 0.015 Significant

*Values are mean±SD of three observations made on 7 day old cultures. Levels are expressed relative to those of the house-keeping gene TUB. **Values are mean±SD of the aflatoxin production by 7-day old cultures of aflatoxigenic clinical and environmental strains.

Leema, Mol Vis 2011; 17:2889-2897. http://www.molvis.org/molvis/v17/a313

©2011 Molecular Vision http://www.molvis.org/molvis/

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