Figure 3. Representative images of Rose Bengal staining of rabbit corneas. The test was unremarkable in normal control rabbits (A), but starting at 2 weeks of pregnancy, punctate staining (arrows) was observed in the corneas of many rabbits (B). At 3 weeks of pregnancy, the rabbit cornea typically shows a moderate staining (C, arrows). Moderate to severe staining was found in approximately 50% of pregnant rabbits at 4 weeks pregnancy (D). As shown in panel D, one rabbit’s cornea showed prominent punctate staining in every quadrant of the cornea.