Molecular Vision: Sagong, Mol Vis 2011; 17:2808-2817. Table 5

Table 5. Haplotype association analysis between LOXL1 SNPs and XFS/XFG.

Haplotype			Proportion
rs1048661	rs3825942	rs2165241	Case	Control	p value*	*OR (95% CI)**	Adjusted OR (95% CI)**
T	G	C	0.93	0.66	3.352×10⁻¹²	6.61 (3.58–12.22)	7.87 (4.10–15.11)
T	G	T	0.01	0.00	0.723	1.64 (0.10- 26.45)	1.46 (0.09- 23.67)
T	A	C	0.02	0.10	0.002	0.21 (0.07- 0.60)	0.20 (0.07–0.59)
T	A	T	0.01	0.07	0.002	0.08 (0.01- 0.61)	0.06 (0.01–0.49)
G	G	C	0.01	0.05	0.033	0.23 (0.05–1.01)	0.19 (0.04–0.86)
G	G	T	0.03	0.11	0.002	0.24 (0.09–0.64)	0.22 (0.08–0.60)
G	A	T	0	0.02	0.054	NA	NA

LOXL1, Lysyl oxidase-like 1; SNP, single nucleotide polymorphism; XFS, Exfoliation syndrome; XFG, Exfoliation glaucoma; OR, odds ratio; NA; non applicable. The single asterisk indicates the p values and OR ratios derived from comparison of the specific haplotype with all of the other haplotypes. The double asterisk indicates the OR values derived from comparison of each haplotype with other haplotypes, age, sex, RVO, DM, HTN, cardiovascular and cerebrovascular disease.