Table 4 of Sagong, Mol Vis 2011; 17:2808-2817.

Table 4. Allele and genotype association analysis between controls versus unilateral XFS/XFG and controls versus bilateral XFS/XFG.

  Control (n=146) Unilateral XFS/XFG (n=70) Bilateral XFS/XFG (n=19)
SNP Count (proportion) Count (proportion) p value OR (95% CI) Count (proportion) p value OR (95% CI)
rs1048661
Allele
T 188 (0.64) 131 (0.94) 1.044×10−10 8.05 (3.93–16.49) 34 (0.89) 0.001 5.04 (1.736–14.62)
G 104 (0.36) 9 (0.06)     4 (0.11)    
Genotype
TT 64 (0.44) 63 (0.90) 1.110×10-10* 11.53 (4.95–26.86)* 17 (0.89) 0.0001* 11.69 (2.59–52.62)*
GT 60 (0.41) 5 (0.07)     0 (0.00)    
GG 22 (0.15) 2 (0.03)     2 (0.11)    
rs3825942
Allele
G 261 (0.89) 137 (0.98) 0.002 5.52 (1.62–18.06) 38 (1.00) 0.026 NA
A 31 (0.11) 3 (0.02)     0 (0.00)    
Genotype
GG 116 (0.80) 67 (0.96) 0.002* 5.54 (1.62–18.86)* 19(1.00) 0.027* NA*
GA 27 (0.18) 3 (0.04)     0 (0.00)    
AA 3 (0.02) 0 (0.00)     0 (0.00)    
rs2165241
Allele
C 265 (0.91) 139 (0.99) 0.0007 14.16 (1.90–105.32) 36 (0.95) 0.520 1.62 (0.37–7.20)
T 27 (0.09) 1 (0.01)     2 (0.05)    
Genotype
CC 122 (0.84) 69 (0.99) 0.0012* 13.57 (1.808–102.53)* 18 (0.95) 0.248* 3.19 (0.40–25.22)*
CT 21 (0.14) 1 (0.01)     0 (0.00)    
TT 3 (0.02) 0 (0.00)     1 (0.05)    

SNP, single nucleotide polymorphism; XFS, Exfoliation syndrome; XFG, Exfoliation glaucoma; OR, odds ratio; NA; non applicable. The asterisks (*) indicate the p values and OR ratios derived from comparison of the specific genotype with all of the others, i.e., TT versus GT+GG at rs1048661, GG versus GA+AA at rs3825942, CC versus CT+TT at rs2165241.

Sagong, Mol Vis 2011; 17:2808-2817. http://www.molvis.org/molvis/v17/a305

©2011 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535