Table 2 of Sagong, Mol Vis 2011; 17:2808-2817.


Table 2. Allele and genotype association analysis between XFS/XFG versus all controls and XFS/XFG versus controls aged 70 years or above.

  XFS/XFG (n=89) All controls (n=146) Controls aged 70 years or above (n=110)
SNP Count (proportion) Count (proportion) p value OR (95% CI) Count (proportion) p value OR (95% CI)
rs1048661
Allele
T 165 (0.93) 188 (0.64) 5.744×10−12 7.02 (3.80–12.97) 135 (0.61) 5.423×10−13 7.99 (4.27–14.95)
G 13 (0.07) 104 (0.36)     85 (0.39)    
Genotype
TT 80 (0.90) 64 (0.44) 2.066×10-12* 11.39 (5.31–24.42)* 45 (0.41) 1.177×10-12* 12.84 (5.85–28.21)*
GT 5 (0.06) 60 (0.41)     45 (0.41)    
GG 4 (0.04) 22 (0.15)     20 (0.18)    
rs3825942
Allele
G 175 (0.98) 261 (0.89) 0.0003 6.93 (2.09–23.01) 193 (0.88) 6.950×10−5 8.16 (2.43–27.37)
A 3 (0.02) 31 (0.11)     27 (0.12)    
Genotype
GG 86 (0.97) 116 (0.80) 0.0003* 7.11 (2.10–24.08)* 85 (0.77) 9.441×10-5* 8.43 (2.45–28.98)*
GA 3 (0.03) 27 (0.18)     23 (0.21)    
AA 0 (0.00) 3 (0.02)     2 (0.02)    
rs2165241
Allele
C 175 (0.98) 265 (0.91) 0.0011 5.94 (1.35–11.71) 199 (0.90) 0.0011 6.16 (1.81–20.99)
T 3 (0.02) 27 (0.09)     21 (0.10)    
Genotype
CC 87 (0.98) 122 (0.84) 0.0008* 8.58 (1.97–37.16)* 92 (0.84) 9.910×10-4* 8.51 (1.92–37.76)*
CT 1 (0.01) 21 (0.14)     15 (0.14)    
TT 1 (0.01) 3 (0.02)     3 (0.03)