Table 6 of
Yang, Mol Vis 2011; 17:2655-2664. Table 6 of
Yang, Mol Vis 2011; 17:2655-2664.
Table 6. Comparison of genotype and allele frequencies of rs800292, rs4505848, and rs4788084 polymorphisms in patients with AU versus control subjects stratified by HLA-B27 status.
Polymorphism |
HLA-B27-positive anterior uveitis (n=42) |
HLA-B27-negative anterior uveitis (n=56) |
Controls (n=308) |
p-value† |
p-value‡ |
|---|---|---|---|---|---|
| rs800292 (CFH 184G/A) | |||||
| Genotype | |||||
| AA | 3 (7.1) | 7 (12.5) | 48 (15.6) | 0.30§ | 0.31§ |
| AG | 20 (47.6) | 22 (39.3) | 145 (47.1) | ||
| GG | 19 (45.2) | 27 (48.2) | 115 (37.3) | ||
| Allele | |||||
| A | 26 (31.0) | 36 (32.1) | 241 (39.1) | 0.15§ | 0.16§ |
| G | 58 (69.0) | 76 (67.9) | 375 (60.9) | ||
| rs4505848 (KIAA1109 G/A) | |||||
| Genotype | |||||
| GG | 4 (9.5) | 8 (14.3) | 50 (16.2) | 0.24§ | 0.91§ |
| AG | 27 (64.3) | 30 (53.6) | 157 (51.0) | ||
| AA | 11 (26.2) | 18 (32.1) | 101 (32.8) | ||
| Allele | |||||
| G | 35 (41.6) | 46 (41.1) | 257 (41.7) | 0.99§ | 0.90§ |
| A | 49 (58.4) | 66 (58.9) | 359 (58.3) | ||
| rs4788084 (IL27 T/C) | |||||
| Genotype | |||||
| TT | 4 (9.5) | 5 (8.9) | 21 (6.8) | 0.75§ | 0.80§ |
| CT | 18 (42.9) | 21 (37.5) | 126 (40.9) | ||
| CC | 20 (47.6) | 30 (53.6) | 161 (52.3) | ||
| Allele | |||||
| T | 26 (31.0) | 31 (27.7) | 168 (27.3) | 0.48§ | 0.93§ |
| C | 58 (69.0) | 81 (72.3) | 448 (72.7) | ||