Table 4 of Mookherjee, Mol Vis 2011; 17:2618-2627.

Table 4. Allele frequency of rs10038177 with additional controls.



Allele
Patient
subgroup		 Frequency
in Patient
(no. of Chromosomes)		 Frequency
in Control
(no. of Chromosomes)

p-value
OR
(95% CI)		 Relative
risk
(95% CI)
C POAG 0.30 (197) 0.27 (162) 0.141    
  HTG 0.32 (88)   0.002* 1.216 (1.064–2.306) 1.437 (1.139–1.799)
  NON-HTG 0.26 (109)   0.886    
T POAG 0.70 (449) 0.73 (444) 0.141 - -
  HTG 0.68 (144)   0.002 - -
  NON-HTG 0.74(305)   0.886 - -

rs10038177 (c.710+30C>T) was found to be strongly associated with HTG patient group in the first phase of the study. To strengthen the observation, rs10038177 was genotyped in additional 184 controls and the SNP was still found to be strongly associated with HTG patient group. *Significant observation; P-value, OR and Relative Risk has been assessed with respect to C allele.

Mookherjee, Mol Vis 2011; 17:2618-2627. http://www.molvis.org/molvis/v17/a283

©2011 Molecular Vision http://www.molvis.org/molvis/

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